Templated deprotonative metalation of polyaryl systems: Facile access to simple, previously inaccessible multi-iodoarenes
نویسندگان
چکیده
منابع مشابه
Templated deprotonative metalation of polyaryl systems: Facile access to simple, previously inaccessible multi-iodoarenes
The development of new methodologies to affect non-ortho-functionalization of arenes has emerged as a globally important arena for research, which is key to both fundamental studies and applied technologies. A range of simple arene feedstocks (namely, biphenyl, meta-terphenyl, para-terphenyl, 1,3,5-triphenylbenzene, and biphenylene) is transformed to hitherto unobtainable multi-iodoarenes via a...
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Bidirectional metalation of hydrobenzoin: direct access to new chiral ligands and auxiliaries.
A bidirectional ortho metalation of the readily available chiral diol hydrobenzoin has been developed that provides direct access to new ortho-functionalized hydrobenzoin derivatives. This one-pot procedure should broaden the utility of hydrobenzoin as an auxiliary and ligand in asymmetric synthesis.
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ژورنال
عنوان ژورنال: Science Advances
سال: 2017
ISSN: 2375-2548
DOI: 10.1126/sciadv.1700832